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Our Technology Advantage

Do you know?  BioPharma Companies' Single Use Sterile BioReactors 

                                                        costs you $100,000 per casing shells, $3,000 per bag, and the production completion rate is currently only 50%. For a COVII virus vaccine production using monoclonal antibody, this simple system is ideal. SPAGS are air lift fermentor that can produce very high density culture of microorganisms. SPAG Systems guarantee complete sterility.  Can you afford the disaster that can happen in the middle of production operation, and your entire equipment is not recoverable?  SPAG System avoid cross-contamination, and easily recoverable in case of external failure, thus minimizes the damage.  

Don’t risk your investment to an unforeseen failure, which may leads to a catastrophic damage. 

Guaranteed Continuous Sterile Operation with Batch Harvest
Small Footprint

Unlike Green Algae farms that take up vast land and spaces, SPAGS are designed heterotrophic or brown algae cultures. SPAGS, the aerobic fermenter will produce culture that is 20 times denser than that of green algae.  Furthermore, this fermentation technology is not limited by the amount of available sunlight. Growth will be much faster. 

The annual production of net DHA from a pilot plant like this can produce 20 tons of DHA rich extracted oil. Productivity is over 100 times per floor space than that of green algae. It grows like yeast;

the difference between solar sourced energy and using carbon as an energy source to fuel growth.

500 liter SPAGS vs. 250,000 liter pharmaceutical bioreactor

FBP and FPN have developed industry disrupting production methods that are linearly scalable - as the number of SPAGS installed grows, the production quantity grows. The pitfalls of traditional tall fermenters that add complexity in shear stress, air pressure differences, and heterogeneous biomass mix are avoided. To replicate a patent process after it has expired with no renewed R&D, has spelled failure for those who have tried to enter this market.  The production of sustainably produced algal sourced DHA oil and DHA rich biomass seems to have higher hurdles to achieve. FBP’s technology avoids all the traps of traditional fermentation bioreactors.

Merk Bioreactors
Zero Stainless Steel Production System
Reposessed Stainless Steel Bioreactors

Modern medical and pharmaceutical production systems rely on stainless steel materials (like this image).  Our truly unique plastic production system does away with this expensive material requirement.  Stainless steel is not corrosion proof against salty water of natural ocean. Traditional bioreactor designs are over-engineered. and it is still not contamination free. Free yourself from the tyranny and expense of stainless steel.

The critical part of the process is in sterile plumbing.  bacteria migration speed is surprisingly fast.

Cost Advantages
SPAGS w_SmartZYME.jpg

500 liter

Sterile Plastic Airlift FermentorGrowth System

Low CAPEx:  

The material cost of the plastic tank is low, while the availability is abundant. the casing is simple, totally corrosion proof. Your production facility can be located practically anywhere that has access to electricity and water.  

Very High Yield:  

Heterotrophic growth can be 100 times denser than any autotrophic growth condition, Recent study shows any autotrophs can grow in heterotrophic (mixotrophic conditions) as long as necessary nutrients and oxygen are available. No need for race tracks, nor large ponds.  Small footprint production system.

Continuous Operation:

Even though it is classified as single use bioreactor, It is made to operate continuously with batch feed and batch harvesting. with CIP/SIP in place. Without fattening, harvest cycle is 3 days.  SPAG is sterile. delivered gamma irradiated, sealed, ready to be inflated.  Plumbing is sterile welded.

Low Energy Cost Operation:

Contrary to conventional technology, FBP's use of  low air pressure and lack of mechanical stirrer, make this bioreactor system highly energy efficient.

Feeding and Harvesting Formula of DHA algae:           Available from FPN

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